GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs5743030 | 1 | rs5743117 | chr2:190714245 | ASNSD1 | chr2:190526125-190535556:+ | -0.59 | -6.38 | 4.25E-10 | Subcutaneous adipose tissue |
| THCA | cis | rs5743030 | 1 | rs5743202 | chr2:190742666 | ASNSD1 | chr2:190526125-190535556:+ | -0.6 | -5.85 | 8.96E-9 | Subcutaneous adipose tissue |
| THCA | cis | rs5743030 | 1 | rs5743208 | chr2:190743048 | ASNSD1 | chr2:190526125-190535556:+ | 0.54 | 5.86 | 8.48E-9 | Subcutaneous adipose tissue |
| THCA | cis | rs10043228 | 1 | rs57434520 | chr5:115648765 | COMMD10 | chr5:115420727-115628978:+ | 0.39 | 6.08 | 2.39E-9 | Asthma or chronic obstructive pulmonary disease |
| THCA | cis | rs1834481 | 1 | rs5744249 | chr11:112025306 | BCO2 | chr11:112046208-112095421:+ | 0.22 | 4.36 | 1.59E-5 | Interleukin-18 levels |
| THCA | cis | rs1834481 | 1 | rs5744249 | chr11:112025306 | IL18 | chr11:112013976-112034840:- | -0.24 | -4.45 | 1.06E-5 | Interleukin-18 levels |
| THCA | cis | rs1834481 | 1 | rs5744256 | chr11:112022848 | BCO2 | chr11:112046208-112095421:+ | 0.23 | 4.59 | 5.61E-6 | Interleukin-18 levels |
| THCA | cis | rs1834481 | 1 | rs5744256 | chr11:112022848 | IL18 | chr11:112013976-112034840:- | -0.24 | -4.51 | 8.25E-6 | Interleukin-18 levels |
| THCA | cis | rs1834481 | 1 | rs5744258 | chr11:112021767 | BCO2 | chr11:112046208-112095421:+ | 0.23 | 4.54 | 7.15E-6 | Interleukin-18 levels |
| THCA | cis | rs1834481 | 1 | rs5744258 | chr11:112021767 | IL18 | chr11:112013976-112034840:- | -0.24 | -4.54 | 7.12E-6 | Interleukin-18 levels |
| THCA | cis | rs1144333 | 1 | rs5745327 | chr1:76270040 | ACADM | chr1:76190043-76229353:+ | 0.22 | 4.56 | 6.6E-6 | Attention function in attention deficit hyperactive disorder |
| THCA | cis | rs1144333 | 1 | rs5745343 | chr1:76273805 | ACADM | chr1:76190043-76229353:+ | 0.23 | 4.84 | 1.77E-6 | Attention function in attention deficit hyperactive disorder |
| THCA | cis | rs1144333 | 1 | rs5745354 | chr1:76275178 | ACADM | chr1:76190043-76229353:+ | 0.22 | 4.68 | 3.66E-6 | Attention function in attention deficit hyperactive disorder |
| THCA | cis | rs1144333 | 1 | rs5745392 | chr1:76306809 | ACADM | chr1:76190043-76229353:+ | -0.25 | -5.03 | 6.99E-7 | Attention function in attention deficit hyperactive disorder |
| THCA | cis | rs1144333 | 1 | rs5745542 | chr1:76365073 | ACADM | chr1:76190043-76229353:+ | -0.25 | -5.04 | 6.74E-7 | Attention function in attention deficit hyperactive disorder |